Easy Identification of Generalized Common and Conserved Nested Intervals
نویسندگان
چکیده
In this article we explain how to easily compute gene clusters, formalized by classical or generalized nested common or conserved intervals, between a set of K genomes represented as K permutations. A b-nested common (resp. conserved) interval I of size |I| is either an interval of size 1 or a common (resp. conserved) interval that contains another b-nested common (resp. conserved) interval of size at least |I|-b. When b=1, this corresponds to the classical notion of nested interval. We exhibit two simple algorithms to output all b-nested common or conserved intervals between K permutations in O(Kn+nocc) time, where nocc is the total number of such intervals. We also explain how to count all b-nested intervals in O(Kn) time. New properties of the family of conserved intervals are proposed to do so.
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عنوان ژورنال:
- Journal of computational biology : a journal of computational molecular cell biology
دوره 21 7 شماره
صفحات -
تاریخ انتشار 2014